Human OX40L PharmaGenie ELISA Kit (SBRS0960)

This OX40L quantitation reagent from Assay Genie enables researchers to measure soluble human OX40L (TNFSF4/CD252), a TNF superfamily ligand that engages the OX40 receptor on activated T cells. The ligand plays a documented role in costimulatory signaling cascades, making its quantification relevant to studies of T cell activation, immune checkpoint modulation, autoimmune disease mechanisms, and tumor microenvironment characterization.

Validated for cell culture supernatant samples alongside plasma and serum specimens, the assay supports diverse experimental designs ranging from in vitro lymphocyte stimulation work to clinical sample analysis. Each package contains reagents sufficient for 96 individual determinations, accommodating medium-throughput experimental work and parallel sample comparison.

Applications include profiling costimulatory molecule expression in CD4+ and CD8+ T cell populations, monitoring immune responses in vaccine development research, and investigating transplant tolerance models where OX40L blockade has shown experimental promise. The assay produces a measurable optical density read-out that integrates with standard laboratory microplate readers commonly found in immunology and cell biology facilities.