Human ORAI1 ELISA Kit (HUFI07401)

ORAI1 (also called CRACM1) is the pore-forming subunit of the store-operated calcium release-activated calcium (CRAC) channel in the plasma membrane. Activated by STIM1 upon endoplasmic reticulum calcium store depletion, ORAI1 mediates sustained calcium influx that drives downstream signaling in T-lymphocytes, mast cells, platelets, and other cell types. The Assay Genie ELISA kit enables quantitative measurement of human ORAI1 protein for research into this pathway.

Delivered as a complete 96 Assays immunoassay kit for research use only, this product supports investigations across immunology, cell signaling, and ion channel biology. Applications include studies of T-cell activation, mast cell degranulation, platelet aggregation, primary immunodeficiency syndromes linked to ORAI1 mutations, and cancer research on dysregulated store-operated calcium entry.

Compatible with standard laboratory workflows, the kit pairs naturally with patch-clamp electrophysiology, Fura-2 and Fluo-4 calcium imaging, and flow cytometry-based functional assays. Researchers examining the STIM-ORAI signaling axis and NFAT-dependent gene transcription will find this ELISA a valuable tool, with the 96 Assays format supporting mid-throughput experimental designs across academic and industrial settings.