Human OPHN1 (Oligophrenin-1) ELISA KIT (HUFI05005)

The OPHN1 gene encodes Oligophrenin-1, a Rho-GTPase activating protein essential for synaptic plasticity, dendritic spine morphogenesis, and clathrin-mediated endocytosis in neurons. Loss-of-function mutations in OPHN1 cause X-linked intellectual disability, so quantitative measurement of Oligophrenin-1 protein supports research into neurodevelopmental disorders, synaptic signaling, and Rho GTPase pathway biomarkers.

This quantitative immunoassay from Assay Genie is built around a capture-and-detection antibody pair specific to human Oligophrenin-1, enabling researchers to measure endogenous protein in cell culture supernatants and other biological matrices. Each microplate ships with pre-coated wells, biotinylated detection antibody, recombinant standards, streptavidin-HRP conjugate, substrate solution, and wash buffer, providing everything required for the full protocol in a single pack.

Working standards and reagents should be kept refrigerated and protected from light until use, and reconstituted stock vials should be aliquoted to limit freeze-thaw cycles. The assay is intended for research use only in neuroscience, neuropsychiatric disease research, and biomarker discovery workflows.