Human O-6-Methylguanine DNA Methyltransferase (MGMT) ELISA Kit

MGMT is a DNA repair enzyme that removes mutagenic alkyl groups from the O6 position of guanine, and protein-level quantification of MGMT underpins oncology studies where loss of expression, commonly driven by promoter methylation, predicts glioma response to alkylating-agent chemotherapy such as temozolomide. This Assay Genie immunoassay kit quantifies human O-6-Methylguanine DNA Methyltransferase across plasma and serum specimens, tissue homogenate preparations, and other fluid samples, supplied for 96 assays per plate.

The single-use plate supports translational epigenetics workflows, letting researchers correlate MGMT abundance with methylation-specific PCR findings across matched tumor and normal-tissue cohorts. Investigators working on glioblastoma prognosis, alkylating-agent pharmacology, and DNA damage-response pathways can integrate the plate into batched sample processing. Reagents are formulated for research use only and intended for in vitro studies of human specimens, providing a standardised readout for cross-cohort comparison in cancer biology laboratories.