Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit

Built for translational endocrinology and stress-axis research, this NR3C1 protein immunoassay from Assay Genie enables quantitative in vitro measurement of glucocorticoid receptor levels in human research samples. The kit supports neurobiology and metabolic research programs where NR3C1 abundance reflects glucocorticoid signaling activity. Investigators studying HPA axis regulation, cortisol-mediated transcriptional control, and cellular stress responses apply this assay to profile receptor levels across experimental cohorts.

Validated for tissue homogenates, cell lysates, and additional biological matrices, the kit uses a 96-assay format that fits moderate-throughput screening workflows. Each plate supplies the components and standards required to build a calibration curve for interpolating unknown sample concentrations. The product is labeled for research use only and is not cleared for diagnostic procedures.

Common applications include mapping GR expression in cell line models of glucocorticoid resistance, comparing receptor levels across treatment groups in animal tissue cohorts, and supporting translational studies of NR3C1 polymorphisms tied to stress-related phenotypes. Sample preparation typically involves homogenization in an appropriate lysis buffer, clarification by centrifugation, and dilution per the enclosed protocol.