Human NOLC1 ELISA Kit (HUFI07500)

The Assay Genie Human NOLC1 ELISA Kit provides quantitative measurement of nucleolar and coiled-body phosphoprotein 1 (NOLC1), also referred to as NOPP140, a heavily phosphorylated nucleolar protein that participates in rRNA transcription, processing, and ribosome biogenesis. Research applications for this kit include studies of nucleolar stress, RNA polymerase I activity, and altered ribosomal biosynthesis in proliferative disease, since NOLC1 overexpression has been documented in hepatocellular carcinoma tissue and correlates with tumor grade in published oncology studies. The assay uses a microplate-based quantitative format accommodating 96 determinations per plate, and is validated for measurement in human biospecimens, supporting translational research workflows that compare circulating protein levels between healthy and diseased cohorts. Each kit ships with the capture antibody, detection antibody, standards, and buffer reagents needed to perform the assay in a research use only laboratory setting, and components are intended for trained personnel conducting cancer biology, cell biology, or candidate biomarker discovery studies targeting the human NOLC1 protein.