Human NMDA receptor-regulated protein 2 (NARG2) ELISA Kit

Assay Genie's Sandwich ELISA Kit is designed for the precise detection of human NMDA receptor-regulated protein 2 (NARG2) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Using a colorimetric detection method, the assay delivers a detection range of 15.6-1000pg/ml with a sensitivity of 10pg/mL, and is specific for both natural and recombinant human NARG2.

NARG2 is a key protein regulated by the NMDA receptor, with roles in neuronal function and synaptic plasticity. Its dysregulation has been implicated in neurological disorders such as Alzheimer's disease, schizophrenia, and depression, making it a relevant biomarker for research into these conditions. The protein, also known as Little elongation complex subunit 2 (ICE2, with synonyms BRCC1 and NARG2; UniProt Q659A1, ~110kDa), localises to the nucleus and participates in snRNA transcription as part of the little elongation complex.

Reported assay performance includes an Intra CV of 4.7% and Inter CV of 7.3%. Linearity in serum, EDTA plasma, and heparin plasma falls within the stated percentage ranges across serial dilutions from 1:2 to 1:16. For research use only.