Human Niemann Pick Disease Type C2 (NPC2) ELISA Kit

Quantitative immunoassay from Assay Genie for measuring Niemann-Pick C2 protein in human specimens. The kit ships as a complete package containing pre-coated microplate strips, reference standards, detection antibody, enzyme conjugate, wash buffer, substrate solution, and stop reagent, sufficient for 96 individual determinations.

NPC2 is a soluble lysosomal protein that binds cholesterol and related sterols, facilitating their transfer across the lysosomal membrane. Loss-of-function mutations in the NPC2 gene cause Niemann-Pick disease type C, a neurodegenerative lysosomal storage disorder characterized by intracellular lipid accumulation. This ELISA Kit supports research into lipid trafficking, neurodegeneration mechanisms, and lysosomal storage diseases, with applications including disease biomarker studies, patient sample screening, and disease model characterization.

The assay is specific to human NPC2 and accepts a range of sample matrices commonly used in clinical and basic research settings. Intended for in vitro research use only, the workflow supports quantification in cell culture studies, lysosomal protein investigations, and biomarker discovery programs targeting cholesterol-handling disorders.