Human Nicotinamide N-methyltransferase (NNMT) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of human Nicotinamide N-methyltransferase (NNMT) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The assay uses a colorimetric detection method and is intended for research use only.

NNMT is an important enzyme that catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions, a reaction important for biotransformation of many drugs and xenobiotic compounds. Dysregulation of NNMT has been implicated in cancer, metabolic disorders, and neurodegenerative conditions, making it a valuable biomarker for research into energy metabolism, lipid metabolism, and inflammation.

Performance characteristics reported by the manufacturer include a detection range of 0.156-10ng/mL and a sensitivity of 0.054ng/mL, with intra-assay CV of 4.6% and inter-assay CV of 6.8%. The kit shows natural and recombinant human NNMT specificity and is supplied as a Sandwich-format ELISA.