Human NF-kappa-B inhibitor beta (NFKBIB) ELISA Kit

This Sandwich ELISA kit from Assay Genie is designed for the accurate detection of NF-kappa-B inhibitor beta (NFKBIB) levels in human samples, including serum, plasma, and cell culture supernatants. The colorimetric assay offers high sensitivity and specificity for research applications. NFKBIB is a key protein involved in regulation of the NF-Kappa B signaling pathway, which plays a critical role in inflammation, immune response, and cell survival. Dysregulation of this pathway has been linked to cancer, autoimmune disorders, and inflammatory conditions, making NFKBIB a valuable biomarker for studying these diseases and developing potential therapeutic interventions.

The kit has a detection range of 0.156-10ng/mL and a sensitivity of 0.039ng/mL, with an intra-assay CV of 4.3% and inter-assay CV of 8.1%. Specificity is for natural and recombinant human NF-kappa-B inhibitor beta. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Recovery is 98% (range 92-104%) for serum and 100% (range 94-106%) for plasma. The kit is for research use only.

Synonyms for the target include I-kappa-B-beta, Thyroid receptor-interacting protein 9, IkB-B, TR-interacting protein 9, NF-kappa-BIB, IKBB, and TRIP9. UniProt ID: Q15653. The protein is localised to the cytoplasm and nucleus, falls within the immunology research area, and has a molecular weight of 356. NCBIsynonym full names include nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB).