Human Neutrophil Elastase PharmaGenie ELISA Kit (SBRS0919)

The PharmaGenie ELISA from Assay Genie enables quantitative measurement of neutrophil elastase, a 29 kDa serine protease encoded by ELANE and released from azurophilic granules of activated neutrophils. Elevated levels of this enzyme are implicated in chronic obstructive pulmonary disease, cystic fibrosis, acute respiratory distress syndrome, and atherosclerotic plaque destabilization, making it a relevant target for inhibitor screening and biomarker development in translational pharmacology pipelines.

Investigators studying pulmonary inflammation, neutrophil-mediated tissue injury, or elastase inhibitor pharmacology can apply this microplate immunoassay to quantitative readouts from cell culture supernatants and ex vivo patient samples. Using a 100 uL sample volume with human-specific capture and detection antibody pairs, the kit supports pharmacokinetic profiling, disease model characterization, and therapeutic candidate evaluation in research use only workflows. Reagents are shipped refrigerated and should be equilibrated to room temperature before each run to preserve antibody binding activity and inter-assay reproducibility.