Human Neuropilin 1 (NRP1) ELISA Kit

Neuropilin-1 (NRP1) is a single-pass transmembrane glycoprotein that acts as a co-receptor for class 3 semaphorins and specific VEGF isoforms. Researchers use quantitative ELISA-based measurement of circulating and tissue NRP1 levels to investigate tumor angiogenesis, vascular permeability, and immune checkpoint biology. This Assay Genie kit provides a colorimetric microplate-based protocol validated for use with human serum preparations, plasma collections, and tissue homogenate lysates. The assay supports studies on SEMA3A/NRP1 signaling in axon guidance, the VEGF-A/NRP1 axis in endothelial proliferation, and emerging roles of NRP1 as a TGF-β1 binding partner on regulatory T cell populations. Research applications include biomarker discovery in solid tumor cohorts, characterization of the tumor microenvironment, cardiovascular studies of vascular remodeling, and neuroscience investigations of semaphorin-mediated neural circuit formation. Each kit contains pre-coated plate wells and reagents sufficient for 96 determinations, with absorbance measurement performed on a standard plate reader.