Human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) ELISA Kit

A Sandwich ELISA Kit from Assay Genie designed for the quantitative detection of human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2). The assay uses a colorimetric detection method and is reactive with human samples, supporting research in neurosciences and the study of neurotransmission and neuronal activity.

CHRNA2 is a key component of neuronal acetylcholine receptors, and its dysregulation has been linked to neurological disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia, making it a valuable biomarker for studying these conditions and potential therapeutic interventions. The kit detects natural and recombinant human Neuronal acetylcholine receptor subunit alpha-2, with a detection range of 0.625-40ng/mL and a sensitivity of 0.341ng/mL. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. According to the underlying biology, after binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. For research use only.