Human Neurogranin (NRGN) ELISA Kit

Manufactured by Assay Genie, this sandwich ELISA is designed for the quantitative measurement of human Neurogranin (NRGN), also known by the synonyms RC3 and Ng. The kit is reactive with human samples and is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, showing specificity for natural and recombinant human Neurogranin. It is intended for cardiovascular research and is labelled for research use only.

The assay reports a detection range of 78-5000pg/mL and a sensitivity of 34pg/mL. Precision is reported as an intra-assay CV of 4.8% and an inter-assay CV of 8.6%. Recovery in serum averages 80% (range 80-85%) and in plasma 81% (range 80-87%). Neurogranin is a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium and acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling, with a reported molecular weight of 7,618 Da.