Human Neurofilament, Heavy Polypeptide (NEFH) ELISA Kit

The NEFH protein is a 200 kDa structural component of the neuronal cytoskeleton, abundant in myelinated axons. Quantifying circulating NEFH helps researchers monitor axonal injury and neurodegeneration across diverse neurological conditions, including amyotrophic lateral sclerosis (ALS), multiple sclerosis, Charcot-Marie-Tooth disease, Alzheimer's disease, traumatic brain injury, and stroke.

The Assay Genie kit, intended for in vitro research use, handles liquid and tissue-derived specimens from clinical collections and preclinical animal studies. Validated for cross-reactivity with human, mouse, and rat NEFH, the kit uses a 50 µL sample volume per well. Researchers commonly pair NEFH measurements with neurofilament light chain (NfL) readings to gain a more complete picture of neuronal damage. The microplate format supports reproducible results across multiple experimental replicates, with sufficient reagent for the full plate.