Human Neurofascin (NFASC) ELISA Kit

Offered by Assay Genie, this quantitative immunoassay kit measures human Neurofascin (NFASC) protein in research samples. Neurofascin belongs to the L1 family of immunoglobulin cell adhesion molecules and is essential for the assembly and maintenance of the nodes of Ranvier and paranodal axon-glia junctions in the peripheral and central nervous systems.

The kit enables laboratory investigation of demyelinating disease, neuroinflammation, and neuronal development, where Neurofascin isoform expression is altered. NF186 and NF155, the two principal Neurofascin isoforms, are studied for their roles in saltatory conduction, sodium channel clustering, and as autoantibody targets in chronic inflammatory demyelinating polyneuropathy (CIDP) and related neuroimmune disorders. Investigators apply the kit to evaluate NFASC levels in tissue homogenates prepared from experimental models and human biopsy material.

Supplied as a complete reagent kit for in vitro research use only, the assay uses a colorimetric measurement captured on a standard microplate reader. Each pack includes pre-coated plate wells, detection antibodies, standards, and buffers needed to generate a standard curve. The format supports research laboratories, and the kit ships refrigerated to maintain reagent stability. Store reagents as indicated in the package insert, and avoid repeated freeze-thaw cycles of prepared working solutions.