Human Neuroblastoma,Suppression Of Tumorigenicity 1 (NBL1) ELISA Kit

An Assay Genie microplate immunoassay provides the reagents needed to quantify endogenous human NBL1, also called DAN (Differential screening-selected gene Aberrant in Neuroblastoma), a secreted member of the DAN family of bone morphogenetic protein (BMP) antagonists involved in cell growth, differentiation, and developmental signaling. Researchers studying neuroblastoma, renal cell carcinoma, and other malignancies where BMP pathway dysregulation and tumor suppressor function are of interest can apply the kit to tissue homogenates and cell lysates prepared from cultured cells or biopsy material. The format is sufficient for 96 assays and is for research use only, supporting in vitro investigations of BMP pathway biology. Each kit includes a pre-coated plate, detection antibody, recombinant standards, and a detailed protocol with recommended dilutions, wash steps, and assay procedure. NBL1 expression is frequently altered in cancer cell lines and primary tumor tissue, making quantitative measurement a useful tool for biomarker discovery and characterization of secreted BMP antagonists in oncology research.