Human Neuregulin 4 (NRG4) ELISA Kit

Researchers investigating metabolic and hepatic biomarkers can use this Assay Genie quantitative immunoassay to measure Neuregulin 4 (NRG4), an EGF-like signaling peptide of growing interest in metabolic disease studies. Circulating NRG4 levels have been investigated as candidate biomarkers in type 2 diabetes, obesity, insulin resistance, and non-alcoholic fatty liver disease (NAFLD), with reduced concentrations reported in affected cohorts relative to healthy controls.

The kit supports translational work on NRG4's role in brown adipose tissue activation, hepatic lipid metabolism, and adipocyte-macrophage crosstalk. Investigators probing the ErbB4 signaling axis use quantitative NRG4 measurements to correlate ligand abundance with downstream receptor phosphorylation in cell-based and clinical sample workflows.

Each kit provides reagents sufficient for 96 assays in a microplate format. Reconstituted standards are handled at room temperature during the assay workflow, with refrigerated storage of unused components between runs. The assay has been validated for measurement across multiple human sample matrices, including serum and tissue homogenates.

This kit is intended for research use only and supports in vitro studies of NRG4 biology in metabolic, hepatic, and cardiovascular research programs.