Human Neural cell adhesion molecule L1 (L1CAM) ELISA Kit

A sandwich ELISA kit from Assay Genie is designed for the quantitative detection of human Neural cell adhesion molecule L1 (L1CAM) in research samples. The assay is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and recognises natural and recombinant human L1CAM. Alternative names for the target include CD171, N-CAM-L1, CAML1 and MIC5.

Reported performance characteristics include a sensitivity of 0.23ng/mL and a detection range of 0.78-50ng/mL. Intra-assay precision is 5.1% CV and inter-assay precision is 9.2% CV. Linearity across dilutions of 1:2, 1:4, 1:8 and 1:16 (N=5) has been demonstrated in serum (98-108%, 92-101%, 105-105%, 102-111%), EDTA plasma (87-97%, 97-107%, 81-92%, 81-91%) and heparin plasma (85-95%, 113-125%, 100-109%, 85-95%). Recovery averages 96% (range 90-102%) for serum and 98% (range 92-104%) for plasma.

L1CAM functions as a cell adhesion molecule with an important role in the nervous system, including neuron-neuron adhesion, neurite fasciculation and outgrowth of neurites, and binds to axonin on neurons. The associated research area is signal transduction. The kit is for research use only.