Human Netrin receptor UNC5C (UNC5C) ELISA Kit

Assay Genie offers a Sandwich ELISA Kit designed for the quantitative measurement of human Netrin receptor UNC5C, a protein that functions as a receptor for netrin and is required for axon guidance. The kit detects this target in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and uses a colorimetric detection method. It is intended for research use only and supports studies of the target's role in nervous system development, axon repulsion, and related neurological conditions.

Performance characteristics include a detection range of 0.156–10 ng/mL and a sensitivity of 0.056 ng/mL. Intra-assay CV is 5.3% and inter-assay CV is 7.9%. Linearity has been demonstrated in serum, EDTA plasma and heparin plasma samples across dilutions of 1:2, 1:4, 1:8 and 1:16. Recovery averages 100% for serum (range 94–106%) and 102% for plasma (range 96–108%). The kit is specific for natural and recombinant human Netrin receptor UNC5C, and the target protein is catalogued under UniProt accession O95185.

Research applications include studies in the area of cancer, as well as investigations of neurological disorders linked to dysregulation of Netrin receptor UNC5C. Specific storage conditions for individual kit components are provided with the product.