Human NEFL ELISA Kit

From Assay Genie, this Sandwich ELISA Kit employs a colorimetric detection method and is reactive with human samples, supporting research in cell biology. The kit is specifically designed for the precise measurement of neurofilament light chain (NEFL) levels in human samples such as serum, plasma, and cell culture supernatants.

NEFL is a key component of the neuronal cytoskeleton, located in the peripheral and central nervous system, where it plays a role in determining axonal caliber and the conduction velocity of peripheral nerves. NEFL levels in body fluids have been linked to neurodegenerative diseases such as Alzheimer's, Parkinson's, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Charcot-Marie Tooth disease, providing valuable insights into disease progression and treatment efficacy for researchers exploring potential therapeutic interventions.

Acceptable sample types include serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The kit has a sensitivity of 9.375 pg/mL and a range of 15.625-1000 pg/mL, with storage recommended at 2-8°C for 12 months. Linearity and recovery data are reported for serum, EDTA plasma, and heparin plasma across dilution ratios.