Human NDUFC1 ELISA Kit (HUFI07532)

Mitochondrial respiratory complex I, the entry point of the electron transport chain, relies on nuclear-encoded subunits such as NDUFC1 (NADH:ubiquinone oxidoreductase subunit C1) to support oxidative phosphorylation and ATP production. Quantitative measurement of NDUFC1 in biological research samples underpins investigations of mitochondrial bioenergetics and the molecular pathology of complex I deficiency, which has been implicated in several neurodegenerative and metabolic disorders.

The Assay Genie kit is supplied in a 96-assay configuration and uses a colorimetric ELISA readout intended for research use only. It is validated for use with samples of human origin including serum or plasma, and provides a quantitative signal that integrates into studies of mitochondrial dysfunction, neurodegeneration, metabolic disease, and cellular respiration pathways. Reagent components should be stored refrigerated; refer to the product insert for the exact storage temperature, shelf life, and recommended aliquot handling before first use.

Typical research applications include biomarker validation, pathway-focused studies of the mitochondrial respiratory chain, and panel-based workups alongside other complex I subunits. Researchers investigating Parkinson's disease, Leigh syndrome, and related conditions frequently include NDUFC1 in subunit panels to characterise assembly and steady-state levels of complex I.