Human Natriuretic Peptide Receptor 2 (NPR2) ELISA Kit

Built for quantifying human Natriuretic Peptide Receptor 2 (NPR2), this colorimetric ELISA kit from Assay Genie supports research into the C-type natriuretic peptide (CNP) signaling axis. NPR2 is a membrane-bound guanylyl cyclase that acts as the principal receptor for CNP, regulating endochondral ossification, chondrocyte proliferation, and long-bone growth. Loss-of-function mutations in NPR2 cause acromesomelic dysplasia, and altered NPR2 activity is implicated in cardiovascular, reproductive, and skeletal biology research.

Configured for 96 assays, the kit is validated with human tissue homogenates, cell lysates, and comparable sample matrices. It enables studies of CNP/NPR2 pathway involvement in growth plate biology, downstream cGMP production, and tissue-specific guanylyl cyclase regulation. Researchers comparing NPR2 with NPR1 and NPR3 receptor behavior, or screening modulators of natriuretic peptide signaling, can integrate this assay into their workflow.

Each kit ships with pre-coated plates, assay buffers, and calibrated standards for measuring NPR2 in research samples. The absorbance-based readout is compatible with standard microplate readers, and the kit is intended for research use only.