Human NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) ELISA Kit

Quantitative measurement of human NACHT, LRR and PYD domains-containing protein 3 (NLRP3) supports inflammation and innate immunity research, and the Assay Genie ELISA Kit delivers a 96-assay workflow suited to mid-throughput biomarker studies. NLRP3 nucleates inflammasome assembly and drives caspase-1-dependent release of IL-1β and IL-18, so the assay is widely used to investigate sterile inflammation, damage-associated molecular pattern signaling, and chronic disease contexts including atherosclerosis, type 2 diabetes, gout, and cryopyrin-associated periodic syndromes. Researchers studying gain-of-function NLRP3 variants, macrophage or monocyte priming, and epithelial inflammasome activation rely on the kit to compare baseline expression against stimulated cellular states. Compatible inputs span whole blood derivatives, tissue homogenates, and cell lysates from human donors, supporting both clinical cohort screening and mechanistic work in cultured primary cells or differentiated lines. The kit ships with absorbance-based readout reagents, standard curves, and pre-coated microplate wells; users often pair the assay with downstream western blot, qPCR, or caspase-1 activity measurements to confirm inflammasome engagement. Reagents arrive refrigerated and remain stable through the printed expiry when stored under cool, dark conditions.