Human N-terminal propeptide of Collagen alpha-1 (III)chain (PIIINP) ELISA Kit

Assay Genie provides a Sandwich ELISA Kit developed for the quantitative measurement of the N-terminal propeptide of Collagen alpha-1(III) chain (PIIINP) in human samples. The assay is reactive with human specimens and is intended for research use only, with specificity directed at natural and recombinant human N-terminal propeptide of Collagen alpha-1(III) chain.

According to the manufacturer's specifications, the kit offers a detection range of 0.312–20 ng/mL and a sensitivity of 0.11 ng/mL. Reported precision includes an intra-assay CV of 4.5% and an inter-assay CV of 7.1%. Recovery values are listed for serum (average 98%, range 92–104%) and plasma (average 100%, range 94–106%).

The kit is validated for use with serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. PIIINP is described in the manufacturer's literature as a marker of collagen synthesis and turnover, with changes in its levels linked to liver fibrosis, cirrhosis and certain types of arthritis, supporting research into collagen metabolism and connective tissue integrity.