Human N-Sulfoglucosamine Sulfohydrolase (SGSH) ELISA Kit

Built for quantitative work on the lysosomal enzyme N-sulfoglucosamine sulfohydrolase, this immunoassay kit from Assay Genie is calibrated for human reactivity and supports research into mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), a lysosomal storage disorder characterized by deficient SGSH activity and progressive heparan sulfate accumulation in affected tissues.

The kit includes reagents for 96 assays and is validated against tissue homogenates and cell lysates, accommodating lysate preparations from cultured fibroblasts, neural tissue, and patient-derived samples. Laboratories probing enzyme kinetics, genotype-phenotype correlations, and candidate therapies for MPS IIIA rely on consistent quantitative readouts of SGSH protein levels across experimental batches.

Designed for in vitro research use only, the workflow integrates with standard microplate readers and fits into broader biochemical pipelines investigating sulfatase biology and glycosaminoglycan catabolism. To preserve reagent stability, laboratories should refrigerate the kit upon receipt, protect components from light, and avoid repeated freeze-thaw cycles of working aliquots.