Human MYRIP (Rab effector MyRIP) ELISA KIT (HUFI05031)

This quantitative immunoassay from Assay Genie measures human MYRIP, the Rab27A-binding scaffold protein that links melanosomes and secretory lysosomes to myosin-Va motors in melanocytes and retinal pigment epithelium. Because MYRIP couples Rab GTPase signaling to actin-dependent vesicle transport, quantifying its levels in human specimens supports research into pigment granule biology, retinal phagosome maturation, and trafficking-related ocular disorders.

Built around an absorbance-based readout on a 96-assay microplate, the kit provides pre-coated wells, lyophilized standards, detection antibody, substrate, and wash buffer sufficient to generate a standard curve and run unknown samples alongside prepared controls. Reconstituted standards and detection reagents should be kept refrigerated and protected from repeated freeze-thaw cycles to preserve binding activity, while the sealed plate and concentrated buffers are supplied ready for immediate workflow integration.

Investigators working on Rab GTPase signaling, melanosome biogenesis, or RPE cell biology can pair this ELISA with downstream western blot, immunohistochemistry on matched donor tissue, or qPCR to localize MYRIP within pigmented cells and resolve transcriptional versus post-translational regulation. The kit is intended for research use only and is not cleared for diagnostic or therapeutic applications.