Human Myosin-Ib (MYO1B) ELISA Kit

Designed by Assay Genie, this Sandwich ELISA Kit enables the detection of Human Myosin-Ib (MYO1B) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids using a colorimetric ELISA method. The assay is specific for natural and recombinant human Unconventional myosin-Ib and is intended for research use only.

MYO1B is a member of the myosin family involved in cell motility, membrane trafficking, and cytoskeletal organization. Dysregulation of MYO1B has been linked to cancer, autoimmune disorders, and neurological conditions, making it a biomarker of interest in these disease areas. The protein acts as a motor that may participate in processes critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport. Recorded synonyms for the analyte include MYH-1c, Myosin I alpha, and MMI-alpha.

Key performance specifications reported by Assay Genie include a detection range of 1.56-100ng/mL, a sensitivity of 0.78ng/mL, an intra-assay CV of 4.3% and an inter-assay CV of 7.1%. Reported linearity spans serum, EDTA plasma and heparin plasma across 1:2, 1:4, 1:8 and 1:16 dilutions, and recovery averages 91% (range 85-97%) for serum and 93% (range 87-99%) for plasma.