Human Myosin Heavy Chain 9, Non Muscle (MYH9) ELISA Kit

This enzyme-linked immunosorbent kit from Assay Genie provides quantitative measurement of non-muscle myosin IIA in clinical research specimens, supporting studies of platelet biology, cytoskeletal dynamics, and glomerular filtration. MYH9 encodes the heavy chain of non-muscle myosin IIA, a cytoskeletal motor protein expressed in platelets, leukocytes, endothelial cells, and renal podocytes, and is the gene most frequently implicated in autosomal dominant MYH9-related disorders such as May-Hegglin anomaly, Fechtner syndrome, Sebastian syndrome, and Evans syndrome, all of which feature macrothrombocytopenia and characteristic Döhle-like leukocyte inclusions. Research applications therefore include investigations of sensorineural hearing loss, cataractogenesis, and progressive nephropathy associated with MYH9 mutations. The microplate-based immunoassay is supplied in an in vitro diagnostic format intended for research use only, with reagents packaged in sealed vials and shipped refrigerated to preserve activity on arrival.