Human Myeloid Differentiation Factor 88 (MyD88) ELISA Kit

Quantitative immunoassay from Assay Genie for measuring human Myeloid Differentiation Factor 88 (MyD88) in cell lysates and tissue homogenates. MyD88 is the central cytoplasmic adapter of the MyD88-dependent signaling cascade, recruited to Toll-like receptors (TLR1, TLR2, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10) and to IL-1 receptor, IL-18 receptor, and IL-33 receptor family members. Its recruitment triggers IRAK kinase activation, IκB degradation, and NF-κB translocation, producing the pro-inflammatory cytokine output that shapes innate and adaptive immune responses. Researchers working on sepsis, autoinflammatory disease, mucosal immunity, vaccine adjuvant biology, and TLR pathway dysregulation use this kit to quantify endogenous MyD88 protein across experimental conditions. The 96-assay plate format supports batched processing with standard curves run in parallel on the same plate, and absorbance values are read on a standard microplate reader. For research use only.