Human Myeloblastin (PRTN3) ELISA Kit

Assay Genie provides a Sandwich ELISA kit for the accurate detection of human Myeloblastin (PRTN3), also known as Proteinase 3, a key enzyme of the immune system that operates particularly in neutrophil function. According to the manufacturer, myeloblastin is a polymorphonuclear leukocyte serine protease, and elevated levels have been associated with inflammatory conditions, autoimmune diseases, and leukemia, supporting research into these disorders and related therapeutic development.

The assay has a detection range of 0.156–10 ng/mL and a sensitivity of 0.056 ng/mL. Reported precision values are an intra-assay CV of 4.3% and an inter-assay CV of 6.2%. Recovery in serum averages 89% (range 83–95%) and in plasma averages 91% (range 85–97%). Linearity has been demonstrated at dilution ratios of 1:2, 1:4, 1:8, and 1:16 in serum, EDTA plasma, and heparin plasma.

The kit is intended for serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids, and is specific for natural and recombinant human Myeloblastin. According to the manufacturer's information, PRTN3 (UniProt P24158) has a molecular weight of 27,807 Da and belongs to the peptidase S1 family, elastase subfamily. The product is for research use only.