Human Myc box-dependent-interacting protein 1 (BIN1) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for the accurate quantification of Human Myc box-dependent-interacting protein 1 (BIN1) in human samples, including serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. The assay uses a colorimetric detection method and demonstrates specificity for natural and recombinant human BIN1.

Performance characteristics include a detection range of 0.156–10 ng/mL and a sensitivity of 0.034 ng/mL. Intra-assay CV is 6.5% and inter-assay CV is 11.6%. Linearity was confirmed in serum (87–115%), EDTA plasma (88–120%), and heparin plasma (89–120%) across dilution factors from 1:2 to 1:16. Recovery ranges from 95–107% in serum (average 101%) and 97–109% in plasma (average 103%). For research use only, the kit supports studies in cancer research; BIN1 is implicated in membrane trafficking and endocytosis, and may act as a tumor suppressor, with dysregulation linked to cancer, cardiovascular disease, and Alzheimer's disease.