Human Muscarinic acetylcholine receptor M3 (CHRM3) ELISA Kit

A sandwich ELISA from Assay Genie is designed for the accurate and sensitive detection of human Muscarinic acetylcholine receptor M3 (CHRM3) levels in human serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit offers high sensitivity and specificity, supporting reliable and reproducible results across a range of research applications.

CHRM3 is a G-protein coupled receptor that mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides, and modulation of potassium channels through the action of G proteins. It plays a crucial role in smooth muscle contraction, CNS function, and neuronal signaling, and its dysregulation has been implicated in Alzheimer's disease, asthma, and gastrointestinal disorders, making it an important target for research and potential therapeutic investigation.

Reported performance characteristics include a detection range of 0.312-20ng/mL, a sensitivity of 0.173ng/mL, an intra-assay CV of 3.2%, and an inter-assay CV of 6.9%. The assay recognises natural and recombinant human Muscarinic acetylcholine receptor M3, falls within the Neurosciences research area, and is intended for research use only.