Human Mucin-20 (MUC20) ELISA Kit

From Assay Genie, this Human Mucin-20 (MUC20) ELISA Kit is a Sandwich ELISA designed for the quantification of MUC20 levels in human samples. The kit is reactive with human samples and is validated for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It is specific for natural and recombinant human Mucin-20.

The assay has a detection range of 0.78-50ng/mL with a sensitivity of 0.32ng/mL. Precision is reported with an intra-assay CV of 4.1% and inter-assay CV of 8.0%. Recovery in serum averaged 101% (range 95-107%) and in plasma averaged 103% (range 97-109%).

MUC20 is a mucin protein that plays a crucial role in maintaining mucosal integrity and functions as a protective barrier in the body. Dysregulation of MUC20 has been linked to various diseases, including inflammatory bowel disease, cystic fibrosis, and certain cancers. According to the source, it may regulate the MET signaling cascade, decreasing hepatocyte growth factor (HGF)-induced transient MAPK activation, blocking GRB2 recruitment to MET to suppress the GRB2-RAS pathway, and inhibiting HGF-induced proliferation of MMP1 and MMP9 expression. The protein is catalogued at UniProt entry Q8N307. For research use only.