Human MTH1/NUDT1 ELISA Kit

Designed for the precise quantification of MTH1 (NUDT1) in human samples, this Sandwich ELISA from Assay Genie uses a colorimetric, double-antibody detection format. The assay is reactive with human samples and accepts a range of starting materials, including serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples.

MTH1 (NUDT1) is an enzyme that helps maintain genomic integrity by hydrolyzing oxidized nucleotides, thereby protecting cells from oxidative stress–induced DNA damage. Dysregulation of the protein has been implicated in cancer, neurodegenerative disorders, and age-related conditions, so monitoring its levels can support research into disease mechanisms and potential therapeutic targets. The kit is grouped under the cell biology research area.

Manufacturer-stated performance figures include a sensitivity of 0.469 ng/mL and a working range of 0.781–50 ng/mL, with kit reagents stored at 2–8°C for 12 months. Reported linearity in serum spans 82–100% across 1:2 to 1:8 dilutions (n=5), with EDTA plasma at 85–102% and heparin plasma at 82–100%. Mean recovery is 98% for serum, 93% for EDTA plasma, and 94% for heparin plasma (n=5).