Human MT1M (Metallothionein 1M) CLIA Kit (HUES00404)

Assay Genie offers a chemiluminescence-based CLIA kit designed for the quantitative determination of Human MT1M (Metallothionein 1M) in serum, plasma and other biological fluids. Built on the Sandwich-CLIA principle, the assay uses a pre-coated micro CLIA plate together with a biotinylated detection antibody and an Avidin-Horseradish Peroxidase (HRP) conjugate, with signal read as Relative Light Units (RLU) on a chemiluminescence immunoassay analyzer.

The kit delivers a sensitivity of 0.47 ng/mL and a detection range of 0.78-50 ng/mL, with a total assay time of 4.5h and a recommended sample volume of 100μL. MT1M is a metal-binding protein that plays a crucial role in protecting cells from heavy metal toxicity and oxidative stress and is involved in metal homeostasis, detoxification, and cell proliferation. It has been implicated in diseases such as cancer, neurodegenerative disorders, and liver diseases, making it a valuable biomarker for research into these conditions.

Both intra-CV and inter-CV are < 15%, supporting reliable reproducibility, and the kit recognizes Human MT1M with no significant cross-reactivity or interference between Human MT1M and analogues. It applies to the in vitro quantitative determination of Human MT1M concentrations in serum, plasma and other biological fluids.