Human MRE11 ELISA Kit (HUFI07572)

Harness quantitative detection of MRE11 (Meiotic Recombination 11 Homolog 1), a core nuclease of the MRN complex (MRE11-RAD50-NBS1) that recognizes and processes DNA double-strand breaks. This Assay Genie kit supports research into genomic instability, ATM-dependent DNA damage signaling, radiosensitivity, and tumorigenesis, with particular relevance to lymphoma, breast cancer, and ataxia-telangiectasia-like disorder (ATLD) studies. Quantitative measurement of MRE11 levels supports longitudinal monitoring of treatment response across oncology workflows.

The human-specific capture antibody pair provides selectivity over closely related nucleases, with minimal cross-reactivity reported against off-target analytes. Reagents are supplied in a microplate format and intended for research use only; they should be stored refrigerated and equilibrated to room temperature before initiating the assay. Compatible with standard ELISA plate readers at the assay working wavelength.