Human MPC2 ELISA Kit (HUFI07587)

The mitochondrial pyruvate carrier subunit MPC2 sits in the inner mitochondrial membrane and gates pyruvate import into the matrix, where it commits carbon to oxidative decarboxylation. Dysregulation of MPC2 has been linked to altered tumor bioenergetics and to models of insulin resistance, so quantitative measurement of circulating MPC2 supports translational research into cancer metabolism and metabolic disease.

Assay Genie offers this Human MPC2 ELISA Kit as a complete reagent set configured for 96 Assays, supplied in a single ready-to-use box containing pre-coated microplate wells, calibrator standards, detection reagents, and substrate. The procedure is a quantitative immunoassay calibrated against recombinant human MPC2 and is intended for research use only; it is not cleared for clinical diagnosis.

In the lab, the kit supports studies of mitochondrial pyruvate flux, screening of pharmacological modulators of pyruvate transport in cell culture systems, and parallel comparison with western blot or PCR readouts from matched tissue specimens. Because MPC2 heterodimerizes with MPC1 to form the active carrier, researchers often pair the assay with MPC1 quantification to assess carrier stoichiometry under different metabolic challenges.