Human/Mouse/Rat Phospho-TrkB (Y816) PharmaGenie ELISA Kit (SBRS2005)

This phosphorylation ELISA from Assay Genie targets the Y816 residue on the TrkB receptor, a key autophosphorylation site that is recruited upon Brain-Derived Neurotrophic Factor (BDNF) binding. Phosphorylation at Y816 generates a docking site for phospholipase C-gamma 1 (PLC-gamma 1), activating downstream cascades that govern neuronal survival, dendritic growth, and synaptic plasticity in the central nervous system.

Researchers use this microplate-based kit to quantify activated TrkB levels in cell lysates and tissue lysates from human, mouse, and rat samples, supporting studies in neuroscience, neurodegeneration, and neurotrophic factor signaling research. All kit components are supplied refrigerated and the microplate is provided in a strip-well format. For research use only; not for diagnostic procedures.