Human/Mouse/Rat Phospho-Beclin-1 (S234) PharmaGenie ELISA Kit (SBRS1761)

Assay Genie's Phospho-Beclin-1 (S234) ELISA Kit enables quantitative detection of Beclin-1 phosphorylated at serine 234 in human samples, with cross-reactivity toward mouse and rat phospho-Beclin-1. Beclin-1 is a core component of the class III PI3K complex that drives autophagosome nucleation, and S234 phosphorylation modulates its activity during nutrient stress, mTOR inhibition, and AMPK signaling. Researchers investigating autophagy flux, neurodegeneration models, tumor cell survival pathways, or metabolic disease can apply this 96-assay microplate kit to cell lysates and tissue lysates for time-course and treatment-condition studies. The kit includes pre-coated wells, phospho-specific detection reagents, and substrate for absorbance-based quantification. Storage at 4 °C is recommended for unopened components, with repeated freeze-thaw cycles of working standards avoided to preserve phospho-epitope integrity. Intended for research use only in ELISA-based phospho-protein signaling studies.