Human Monocarboxylate transporter 1 (SLC16A1) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of human Monocarboxylate transporter 1 (SLC16A1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, using a colorimetric detection method.

SLC16A1, also known as monocarboxylate transporter 1, is a proton-coupled transporter that catalyses the rapid movement of monocarboxylates such as lactate, pyruvate, branched-chain oxo acids and ketone bodies across the plasma membrane. It plays a critical role in lactate transport and energy metabolism, and its dysregulation has been implicated in cancer, diabetes and metabolic disorders, making it a relevant target for therapeutic and biomarker research.

Manufacturer-reported performance includes a detection range of 78-5000 pg/mL, a sensitivity of 42.2 pg/mL, an intra-assay CV of 7.5% and an inter-assay CV of 10.8%. Spike-and-recovery averaged 100% (94-106%) in serum and 102% (96-108%) in plasma. The kit is specific for natural and recombinant human MCT1 (UniProt P53985) and is intended for research use only.