Human MNK1 ELISA Kit (HUFI07599)

Quantify MAP kinase interacting serine/threonine kinase 1 (MNK1) in research samples with this ELISA Kit from Assay Genie. MNK1 is a key effector of the MAPK signaling cascade, phosphorylating eukaryotic translation initiation factor 4E (eIF4E) at Ser209 to regulate cap-dependent mRNA translation. Dysregulated MNK1 activity is implicated in oncogenic transformation, cytokine-driven inflammation, and synaptic plasticity, making this target valuable for cancer biology, immunology, and neuroscience research. The kit supports studies of translation regulation, Ras/MAPK pathway activation, and tumor signaling in human-derived samples, including cell lysates and tissue homogenates. Its 96 Assays format enables medium-throughput screening of experimental cohorts, with pre-coated wells, detection antibodies, and standard diluents provided for a full plate run. Reagents should be stored according to the supplied insert, with components equilibrated to room temperature before initiating the assay. Researchers investigating leukemia, breast, and lung tumor models find this kit useful for tracking MNK1 protein abundance alongside phospho-eIF4E readouts.