Human MKRN1 (E3 ubiquitin-protein ligase makorin-1) ELISA KIT (HUFI05083)

Makorin-1, encoded by the MKRN1 gene, is an E3 ubiquitin-protein ligase and ribonucleoprotein studied in oncology, cell signaling, and protein homeostasis research. The Assay Genie Human MKRN1 ELISA Kit is a quantitative immunoassay providing the reagents needed to measure endogenous human makorin-1 levels in research specimens. The kit is supplied as a complete set including pre-coated plate wells, ready-to-use standards, detection antibody, and substrate solution, packaged in a single kit box sized for a 96-assay microplate workflow.

This colorimetric assay is read on a standard microplate reader and is compatible with common ELISA instrumentation used in life science laboratories. Reagents are stored refrigerated at 4°C and should be protected from light to maintain activity through the stated shelf life; the procedure is intended for research use only. Sample handling accommodates serum-derived samples and plasma-derived specimens as well as cell lysates collected under standard laboratory conditions. MKRN1 has been implicated in p53 pathway regulation, telomere maintenance, and ubiquitin-dependent turnover of substrates including cell cycle regulators and apoptotic signaling proteins, supporting the kit's utility for studies in cancer biology, molecular signaling, and gene expression analysis.