Human Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A) ELISA Kit

From Assay Genie, this sandwich ELISA kit with colorimetric detection is designed for the quantitative detection of human Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. MAP1LC3A is a ubiquitin-like modifier involved in autophagy, the cellular process that degrades and recycles damaged organelles and proteins to maintain cellular homeostasis; dysregulation of autophagy has been linked to cancer, neurodegenerative disorders and infectious diseases, making MAP1LC3A a useful biomarker for research into these conditions and potential therapeutic interventions.

The kit is intended for research use only and is reactive with human samples, with stated specificity for natural and recombinant human MAP1LC3A. The reported detection range is 0.156-10ng/mL with a sensitivity of 0.098ng/mL. Reported intra-assay CV is 5.1% and inter-assay CV is 8.5%. Linearity has been characterised in serum, EDTA plasma and heparin plasma across dilutions from 1:2 to 1:16. Recovery is reported as an average of 86% (range 80-92%) for serum and 88% (range 82-94%) for plasma. The kit is associated with UniProt entry Q9H492 and the listed research area is cancer.