Human METTL3 ELISA Kit (HUFI07629)

Methyltransferase-like 3 (METTL3) is the catalytic core of the m6A RNA methyltransferase complex, and quantitative measurement of this enzyme is essential for research into RNA epigenetics, post-transcriptional gene regulation, and tumor biology. The Assay Genie kit for human METTL3 is supplied in a 96 Assays format and is intended for research use only.

METTL3 deposits N6-methyladenosine marks on messenger RNA, microRNA, and long non-coding RNA substrates, and aberrant METTL3 expression has been documented in acute myeloid leukemia, glioblastoma, hepatocellular carcinoma, lung adenocarcinoma, and breast cancer. Investigators in oncology, stem cell biology, and RNA metabolism use this kit to monitor enzyme abundance across cell culture models, primary tissue lysates, and translational study cohorts.

Each kit includes assay plates, detection reagents, and standards required to run the full plate following the included protocol. Components can be processed in parallel for higher-throughput screening of METTL3 modulators, validation of candidate biomarkers, and characterization of m6A pathway activity in relevant disease models.