Human METTL1 ELISA Kit (HUFI07627)

Targeted quantification of human METTL1 supports research into m7G tRNA methyltransferase biology, codon-biased translation, and cancer-associated epitranscriptomic dysregulation. METTL1 catalyzes the N7-methylguanosine modification at position 46 of tRNA in complex with the auxiliary factor WDR4, and altered METTL1 expression has been documented across hepatocellular carcinoma, acute myeloid leukemia, and several solid tumor models, making reliable protein-level measurement relevant to translational oncology workflows. The Assay Genie immunoassay provides a 96 Assays plate format configured for an absorbance-based read-out, accommodating serum-derived and plasma-derived specimens from human donors. Research applications include screening patient cohorts for METTL1 biomarker potential, monitoring expression changes during stem cell differentiation and neurodevelopment studies, and pairing protein-level quantification with downstream tRNA modification profiling or codon-usage analyses. Each kit is supplied as a complete package suited to laboratory workflows in RNA epitranscriptomics, cancer biology, and neuroscience, where METTL1 activity and WDR4 partner status are investigated alongside translational control mechanisms.