Human Methionine Adenosyltransferase II Alpha (MAT2a) ELISA Kit

MAT2A is the catalytic subunit of methionine adenosyltransferase that synthesizes S-adenosylmethionine (SAM), the universal methyl donor driving cellular methylation reactions governing lipid metabolism, neurotransmitter synthesis, and epigenetic DNA and histone modification. The Assay Genie Human Methionine Adenosyltransferase II Alpha (MAT2a) ELISA Kit enables quantitative measurement of MAT2A protein in human samples using an absorbance-based readout.

The enzyme is widely investigated in oncology research, particularly in MTAP-deficient cancers where MAT2A becomes essential and represents a therapeutic vulnerability. Investigators studying liver biology, methionine cycle dysregulation, homocysteine metabolism, and one-carbon metabolism pathways also rely on MAT2A quantification in cell-based and tissue-based experiments.

Validated for tissue homogenates and cell lysates, the kit is reactive against human MAT2A and supplied as a complete 96-assay package containing a pre-coated microplate, recombinant standards, detection reagents, and assay buffers. Researchers commonly apply this kit to primary cell cultures, treated cell lines, and xenograft tissue samples to track MAT2A expression changes under pharmacological or genetic perturbation.