Human Metalloproteinase inhibitor 3 (TIMP3) ELISA Kit

A sandwich ELISA kit from Assay Genie for the quantitative measurement of human Metalloproteinase inhibitor 3 (TIMP3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay uses a colorimetric detection method and is reactive with human samples, with specificity directed against natural and recombinant human Metalloproteinase inhibitor 3.

Reported performance specifications include a detection range of 3.12-200ng/mL, a sensitivity of 0.39ng/mL, intra-assay CV of 6.1% and inter-assay CV of 8.4%. TIMP3 is a secreted regulator of the extracellular matrix that complexes with metalloproteinases such as collagenases and irreversibly inactivates them by binding to their catalytic zinc cofactor; it is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. The kit is listed for cancer research applications and is intended for research use only.