Human Membrane Cofactor Protein (MCP) ELISA Kit

A quantitative in vitro ELISA kit from Assay Genie for measuring human Membrane Cofactor Protein (MCP, also known as CD46) in research samples, using a colorimetric readout compatible with standard microplate readers. MCP is a widely expressed type I transmembrane glycoprotein that acts as a cofactor for factor I-mediated cleavage of C3b and C4b, protecting autologous cells from complement-mediated damage. The assay supports studies in complement immunology, atypical hemolytic uremic syndrome, transplant rejection, reproductive immunology, and investigation of viral entry mechanisms, since MCP also serves as a receptor for several pathogens including measles virus and certain adenoviruses.

Supplied in a 96 assays configuration with reactivity confirmed against human samples, the kit fits workflows focused on complement regulatory pathways, autoimmune disease biomarkers, and host-pathogen interaction research. Each kit includes the reagents required to run the assay, and the protocol follows a standard ELISA workflow that integrates easily into existing immunology or nephrology research pipelines. The format makes it straightforward to quantify soluble or shed MCP across disease models and patient-derived samples.