Human Melanin-concentrating hormone receptor 1 (MCHR1) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the quantitative detection of human Melanin-concentrating hormone receptor 1 (MCHR1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay has a stated sensitivity of 0.12 ng/mL and a detection range of 0.312-20 ng/mL, with intra-assay CV of 5.1% and inter-assay CV of 8.9%. Specificity covers natural and recombinant human MCHR1.

MCHR1 is a G-protein coupled receptor that binds melanin-concentrating hormone and signals through G proteins that inhibit adenylyl cyclase as well as G proteins that activate phosphoinositide hydrolysis. It is implicated in the regulation of feeding behavior and energy homeostasis, and its dysregulation has been linked to obesity, depression and addiction, making it a target of interest in metabolic and neuropsychiatric research. For research use only.